Clinical Trials Directory

Trials / Terminated

TerminatedNCT05920408

Study to Assess EXS21546 in Combination in Patients With Advanced Solid Tumours

A Phase 1B/2A Study to Assess the Safety, Tolerability, Pharmacokinetic and Anti-tumoral Activity of EXS21546 in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumours

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
6 (actual)
Sponsor
Exscientia AI Limited · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A phase 1B/2A study to assess the safety, tolerability, pharmacokinetic and anti-tumoral activity of EXS21546 in combination with a PD-1 inhibitor in patients with advanced solid tumours.

Detailed description

A phase 1B/2A study to assess the safety, tolerability, pharmacokinetic and anti-tumoral activity of EXS21546 in combination with a PD-1 inhibitor, nivolumab, in patients with advanced solid tumours, non small cell lung cancer and renal cell carcinoma.

Conditions

Interventions

TypeNameDescription
DRUGEXS21546EXS21546 Granule in Capsule

Timeline

Start date
2023-04-11
Primary completion
2023-09-27
Completion
2023-10-23
First posted
2023-06-27
Last updated
2023-11-08

Locations

5 sites across 2 countries: Belgium, France

Source: ClinicalTrials.gov record NCT05920408. Inclusion in this directory is not an endorsement.