NCT05919810

The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Integrative Skin Science and Research · Industry
• Sex: All
• Age: 12 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluates how probiotics and dietary supplementation with an herbal powder can shift the gut microbiome in those with non-cystic acne vulgaris.

Detailed description

The investigators hope to evaluate the effects of oral supplements in changing intestinal health and the gut bacteria in patients with non-cystic acne vulgaris. Acne is a chronic inflammatory condition that is estimated to affect greater than 85% of the population at some point. While antibiotics are typically used for systemic therapy, it can increase the risk for drug-resistant bacteria and shift the gut microbiome in a negative way. On the other hand, probiotics and dietary supplementation have been shown to support the gut microbiome. In this study, participants will be randomized to either receiving a probiotic or powder supplement. This means that participants will have an equal chance of receiving either product as half of the participants will be randomized to receive only oral probiotic, and the other half will receive oral supplement powder.

Conditions

• Acne Vulgaris
• Acneiform Eruptions
• Skin Diseases
• Sebaceous Gland Diseases

Interventions

Type	Name	Description
OTHER	Probiotic	Oral probiotic
DIETARY_SUPPLEMENT	Oral herbal powder supplement	oral herbal powder

Timeline

• Start date: 2023-07-03
• Primary completion: 2024-02-12
• Completion: 2024-07-31
• First posted: 2023-06-26
• Last updated: 2024-12-18

Locations

1 site across 1 country: United States