NCT05919134

The Effect of Probiotics on Gingivitis: Part 2

The Effect of Oral Probiotics Containing Streptococcus Salivarius M18 on Gingivitis and Oral Hygiene: a Randomized Clinical Trial: Part 2

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: I.M. Sechenov First Moscow State Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.

Detailed description

This will be a double-blind, randomized, placebo-controlled two-arm parallel-group study of the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene. The groups will include young adults with gingivitis diagnosed clinically. To assess the effect of oral probiotics, the following parameters will be used: gingival health (gingival index, GI; gingival bleeding index, GBI) and oral hygiene level (the Turesky Modification of the Quigley-Hein Plaque Index, TMQHPI).

Conditions

• Gingivitis; Chronic

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dentoblis	dissolve the tablets in the mouth once a day for 4 weeks
DIETARY_SUPPLEMENT	Placebo	dissolve the tablets in the mouth once a day for 4 weeks

Timeline

• Start date: 2023-04-24
• Primary completion: 2023-09-20
• Completion: 2023-10-12
• First posted: 2023-06-26
• Last updated: 2023-11-21

Locations

1 site across 1 country: Russia