NCT05919043

Upper Limb-based Movement Priming for Lower Limb Neuroplasticity & Motor Recovery in Stroke

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: University of Illinois at Chicago · Academic / Other
• Sex: All
• Age: 40 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to to determine the effect of movement-based priming using the upper limbs on lower limb neuroplasticity and behaviors in chronic stroke. The main questions we aim to answer are: 1. What are the acute effect of UL-priming on lower limb neuroplasticity and motor behaviors in persons with stroke compared to other priming modalities? 2. What are the time effects of UL-priming on neuroplasticity and motor behavior in individuals with stroke? In this cross over study, participants will be involved in three priming sessions involving \- UL-priming using rhythmic, symmetric, bilateral priming involving the movement of at least one major joint in the upper limbs. AND \- Sham priming using auditory stimulation (1 Hz metronome). AND \- Lower-limb movement-based priming using rhythmic, symmetric, dorsiflexion and plantarflexion movements. Researchers will compare outcome measures between the different priming sessions.

Conditions

• Stroke

Interventions

Type	Name	Description
OTHER	Upper limb-based movement priming (UL-priming)	Repetitive upper limb movements administered to the beat of a metronome.
OTHER	Lower limb-based movement priming (LL-priming)	Repetitive lower limb movements administered to the beat of a metronome.
OTHER	Sham priming	Auditory stimulation.

Timeline

• Start date: 2024-07-01
• Primary completion: 2025-06-25
• Completion: 2025-06-25
• First posted: 2023-06-26
• Last updated: 2025-07-02

Locations

1 site across 1 country: United States