NCT05915390

Walnut and Immunity Study

Effects of Walnuts on Innate, Acquired and Gut Immunity in Older Adults With Overweight: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Loma Linda University · Academic / Other
• Sex: All
• Age: 55 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The main objective of the study is to determine if eating walnuts enhances immune function, in older free-living men and postmenopausal women with overweight.

Detailed description

The main objectives of our proposed study are to determine the effect of walnut consumption on innate, acquired, and gut immunity by assessing whether the ingestion of walnuts enhances immune function, in older free-living men and postmenopausal women with overweight. To accomplish these objectives, a randomized controlled, parallel design study is proposed with two groups consuming their habitual diet, but with one (Walnut group) receiving 15% of their total energy as walnuts and the other (Control group) abstaining from eating any walnuts and limited amounts of other tree nuts and peanuts (up to \<1 serving/wk).

Conditions

• Immune Response
• Upper Respiratory Tract Infection

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	walnuts	walnuts will provide 15% of the total energy
DIETARY_SUPPLEMENT	Habitual diet	continue with habitual diet and abstain from walnuts

Timeline

• Start date: 2023-06-27
• Primary completion: 2023-12-18
• Completion: 2023-12-18
• First posted: 2023-06-23
• Last updated: 2024-10-02

Locations

1 site across 1 country: United States