Trials / Not Yet Recruiting
Not Yet RecruitingNCT05914636
Evaluation of Intestinal Microbiota Implication in Ruptured Intracranial Aneurysm
Evaluation of Intestinal Microbiota Implication in Ruptured Intracranial Aneurysm: a Comparison of Ruptured and Unruptured Patient With Taxonomic and Metabolic Evaluation of Microbiota
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- Hospices Civils de Lyon · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The physiopathology of intracranial aneurysm from initiation to ruptured is incompletely understood but included inflammation. The microbiota is known to interact with brain and can promote inflammation. The objective of this study is to describe microbiota with taxonomic and metabolomic analysis. A comparison between ruptured and unruptured intracranial aneurysm will be performed. The study hypothesis is that microbiota is different between ruptured and unruptured patient.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | analysis of foecal microbiota | An analysis of foecal microbiota including taxonomic and metabolomic analysis will be performed and compared between ruptured and unruptured patient. confundens factors as diet, obesity for microbiota and as smoking, hypertension, size for aneurysm ruptured will be sampled and independence will be analyzed. |
Timeline
- Start date
- 2024-08-31
- Primary completion
- 2026-08-31
- Completion
- 2026-08-31
- First posted
- 2023-06-22
- Last updated
- 2024-04-17
Source: ClinicalTrials.gov record NCT05914636. Inclusion in this directory is not an endorsement.