NCT05910047

Supplemental Hydrogen Plus PQQ for Mitochondrial Biomarkers and Brain Function in Elderly With Mild Cognitive Impairment

The Effects of Six-week Hydrogen Plus Pyrroloquinoline Quinone (PQQ) Intake on Mitochondrial Biomarkers, Brain Metabolism and Cognition in the Elderly With Mild Cognitive Impairment

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: University of Novi Sad, Faculty of Sport and Physical Education · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this randomized controlled double-blind parallel-group interventional trial is to evaluate the effects of dietary supplementation with molecular hydrogen and pyrroloquinoline quinone in elderly. The main questions it aims to answer are: (1) whether the supplementation affects biomarkers of mitochondrial function in serum, and (2) whether the supplementation affects cognition and brain metabolism. The participants will be subjected to take the dietary supplement during 6 weeks.

Conditions

• Age-associated Memory Impairment

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Supplement	Dietary supplement containing molecular hydrogen and pyrroloquinoline quinone
DIETARY_SUPPLEMENT	Placebo	Inert substance

Timeline

• Start date: 2023-09-01
• Primary completion: 2024-03-15
• Completion: 2024-03-31
• First posted: 2023-06-18
• Last updated: 2024-12-04

Locations

1 site across 1 country: Serbia