NCT05908552

Topical Cannabis for Chronic Musculoskeletal Pain

A Novel Non-Opioid Topical Therapy for Chronic Musculoskeletal Pain

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 77 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: All
• Age: 21 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Our proposal objective is to evaluate if state-regulated topical CBD-based products relieve chronic musculoskeletal pain and/or absorb into the bloodstream.

Detailed description

The goal of this study is to learn more about the analgesic efficacy of state-regulated topical cannabinoid products (creams, lotions, salves, etc) and to determine if these topical products are absorbed systemically and can be detected in blood samples. Given that state-regulated dispensary products cannot be brought onto the university campus, this observational study design utilizes a Mobile Pharmacology Laboratory that will go to study participants' homes. Blood samples and other assessments will taken in the mobile lab prior to use of a topical cannabinoid product and at several time points afterwards (4 hours, 24 hours, and 2 weeks). Participants will also collect microsamples of blood using a small device at home at three time points during the first 2-72 hours after application of the product.

Conditions

• Chronic Pain
• Musculoskeletal Pain
• Joint Pain

Timeline

• Start date: 2023-07-01
• Primary completion: 2024-04-30
• Completion: 2024-08-31
• First posted: 2023-06-18
• Last updated: 2023-06-18