NCT05908279

Gait Control in Parkinson Disease

Flexible Control of Gait in Parkinson Disease: Effect of Task Instruction on the Exploitation of Redundancy in Speed Control.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Université Catholique de Louvain · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
OTHER	Walking test	Walk with and without a metronome
OTHER	Disease assessement	Disease stage assessed by a doctor

Timeline

• Start date: 2023-05-01
• Primary completion: 2027-10-31
• Completion: 2027-10-31
• First posted: 2023-06-18
• Last updated: 2023-06-18

Locations

1 site across 1 country: Belgium