NCT05906277

Biobanking and New Biomolecular Metrics

Melanoma 4p: Biobanking and New Biomolecular Metrics

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Regina Elena Cancer Institute · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this Interventional study aims to apply, in our Institutes, a 4p oncological model i.e. predictive, personalized, of precision and participated (Regina Elena and San Gallicano).

Detailed description

Patients will be recruited with an innovative and systematic scheme: collection and biobanking of biological materials (tissue biopsy, re-biopsy and liquid biopsy) followed by a molecular monitoring thanks to genomic and epigenomic methods. It's an open-ended study. In particular we will try to identify new "actionable" signatures and we will try to insert the patients to innovative clinical trials, thanks to the evaluation of all cases with a Molecular Tumor Board. The main objectives are: * Introduce a new methodology to improve and integrate the already existent institutional PDTA * Evaluate and measure the applicative value * Establish a biostatistical platform

Conditions

• Melanoma (Skin)
• Liquid Biopsy

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Biopsy	Liquid biopsy, re-biopsy, tissue biopsy

Timeline

• Start date: 2019-01-29
• Primary completion: 2022-12-01
• Completion: 2025-12-31
• First posted: 2023-06-15
• Last updated: 2023-06-15

Locations

1 site across 1 country: Italy