Clinical Trials Directory

Trials / Completed

CompletedNCT05902962

SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects

A Phase 1 Open-Label, Single Arm Dose Escalation Study to Evaluate the Safety and Tolerability of Intravitreally Administered VP-001 in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
17 (actual)
Sponsor
PYC Therapeutics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A Phase 1 Open-Label, Single Arm Dose Escalation Study to Evaluate the Safety and Tolerability of Intravitreally Administered VP-001 in Participants with Confirmed PRPF31 Mutation-Associated Retinal Dystrophy

Conditions

Interventions

TypeNameDescription
DRUGVP-001Phase 1 open-label, single arm dose escalation study of VP-001 in participants with genetically confirmed PRPF31 mutation-associated retinal dystrophy

Timeline

Start date
2023-04-20
Primary completion
2025-10-08
Completion
2025-10-08
First posted
2023-06-15
Last updated
2026-04-13

Locations

6 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05902962. Inclusion in this directory is not an endorsement.

SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (NCT05902962) · Clinical Trials Directory