NCT05901454

Yellow Fever Human Infection Model With YF-17D

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Leiden University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

No antiviral treatment exists for yellow fever, only supportive care, and therefore we rely on prevention through vaccination. Although this vaccine is very effective, stockpiles are insufficient in outbreak situations and some people have a contraindication to be vaccinated. For those who are unprotected and at risk of yellow fever infection, treatment could be life saving.

Detailed description

No antiviral treatment exists for yellow fever, only supportive care, and therefore we rely on prevention through vaccination. Although this vaccine is very effective, stockpiles are insufficient in outbreak situations and some people have a contraindication to be vaccinated. For those who are unprotected and at risk of yellow fever infection, treatment could be life saving.

Conditions

• Yellow Fever

Interventions

Type	Name	Description
DRUG	Yellow Fever Vaccine	vaccination according to manufacturers manual (0.5mL subcutaneously in the arm)

Timeline

• Start date: 2023-02-17
• Primary completion: 2023-07-01
• Completion: 2024-03-01
• First posted: 2023-06-13
• Last updated: 2023-06-13

Locations

1 site across 1 country: Netherlands