NCT05901337

Cupping Therapy on Immune System in Post Covid -19

Influence of Cupping Therapy on Immune System in Post Covid- 19 Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 21 Years – 66 Years
• Healthy volunteers: Not accepted

Summary

Purpose of this study is to investigate 1. The effect of Dry cupping therapy on T-Lymphocyte in post covid-19 patients. 2. The effect of Dry cupping therapy on serum Cytokine in post covid-19 patients. 3. The effect of Dry cupping therapy on Immunoglobulin IgA. 4. The effect of Dry cupping therapy on Immunoglobulin IgM. 5. The effect of Dry cupping therapy on Immunoglobulin IgG. seventy six patients of both genders with deficiency in T-Lymphocyte number,,higher level of serum cytokine and lower immunoglobulin IgA,IgM,IgG after two weeks of recovery from covid-19 . Age range from Twenty one to Sixty six years old .They participated in the study and recruited from surveillance unit of Shobra general hospital .These patients recruited by phone and have been offered to participate in the programme.The patients were divided equally into two groups (A and B). Assessment was done before and after treatment. T-Lymphocyte, serum cytokine and immunoglobulin IgA, IgM and IgG were analyzed by kenza 240 TX from fluorescence-labeled flow cytometry. Disposable cupping therapy instrument was used in treatment of group (A) in addition to traditional medical treatment in the form of vitamin C, D and anticoagulant drugs. Traditional medical treatment only was used in treatment of group (B).The obtained results of this study will determine the significant improvement of participated two groups. .

Detailed description

Patient were selected randomly and distributed in two groups by computer generation. The sample size was calculated using the G\*Power software (version 3.0.10). F-test MANOVA within and between interaction effects was selected. Considering a power of 0.80, an α level of 0.05 (2 tailed) and effect size of 0.39; two groups and response variables of five, a generated sample size of at least 38 participants per group was required and total sample size of 76 subjects.

Conditions

• Covid-19 Patients

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Cupping therapy with convential medical treatment	Device:Cupping therapy device Group A participants received Dry cupping therapy one session per week for 8 weeks with 6 days intervals between sessions and with cups applied to the skin for around 8 minutes. (In addition to convential medical treatment for 8 weeks in the form of : 1. Vitamin D: The recommended dietary dose of vitamin D is 600 IU each day for adults 70 and younger . 2. Vitamine C: The recommended dietary dose 200 mg/day vitamin c 3. Anticoagulation drugs ("blood thinners")Doctors usually prescribe low-molecular-weight heparin (enoxaparin) (30 mg), each given subcutaneously every 12 hours .
DRUG	Convential medical treatment	Group B participants received convential medical treatment for 8 weeks in the form of : 1. Vitamin D: The recommended dietary dose of vitamin D is 600 IU each day for adults 70 and younger . 2. Vitamine C: The recommended dietary dose 200 mg/day vitamin C 3. Anticoagulation drugs ("blood thinners")Doctors usually prescribe low-molecular-weight heparin (enoxaparin) (30 mg), each given subcutaneously every 12 hours .

Timeline

• Start date: 2022-03-07
• Primary completion: 2022-06-21
• Completion: 2023-06-01
• First posted: 2023-06-13
• Last updated: 2023-06-13

Locations

1 site across 1 country: Egypt