Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT05901025

Homologous Recombination Repair Pathway Gene Mutation Spectrum in Chinese Breast Cancer Patients

Homologous Recombination Repair Pathway Gene Mutation Spectrum in Chinese Breast Cancer Patients: A Multi-center, Prospective, Observational Study

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
5,000 (estimated)
Sponsor
Shanghai Jiao Tong University School of Medicine · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The goal of this clinical trial is to learn about the mutation spectrum of homologous recombination repair pathway genes and its instructive significance in the treatment of Chinese breast cancer patients.

Detailed description

The main questions it aims to answer are: 1. What is the mutation spectrum of homologous recombination repair pathway genes in Chinese breast cancer patients? 2. Does homologous recombination repair pathway gene mutation have an impact on patient outcome (breast cancer recurrence, neoadjuvant chemotherapy efficacy, treatment decisions, etc.) ? There is no intervention on participants, but all participants will be given regular follow-up post surgery according to ASCO guidelines.

Conditions

Timeline

Start date
2023-06-05
Primary completion
2028-06-30
Completion
2033-06-30
First posted
2023-06-13
Last updated
2023-06-13

Source: ClinicalTrials.gov record NCT05901025. Inclusion in this directory is not an endorsement.