Clinical Trials Directory

Trials / Enrolling By Invitation

Enrolling By InvitationNCT05897957

Continued Evaluation of Patients With Parkinson's Disease Who Previously Received BRT-DA01

Continued Evaluation of Patients With Parkinson's Disease Who Previously Received BRT-DA01, a Human Embryonic Stem Cell-Derived Midbrain Dopaminergic Neuronal Cell Therapy

Status
Enrolling By Invitation
Phase
Study type
Observational
Enrollment
12 (estimated)
Sponsor
BlueRock Therapeutics · Industry
Sex
All
Age
50 Years – 78 Years
Healthy volunteers
Not accepted

Summary

This is a multicenter study to evaluate the safety and clinical outcomes of BRT-DA01 in subjects with PD who previously received BRT-DA01 in the Phase 1 Study MSK-DA01-101.No investigational therapy will be administered in this study.

Detailed description

All subjects who received BRT-DA01 transplantation in Study MSK-DA01-101 (ie, parent study) will be asked to enroll in Study BRT-DA01-501. Subjects enrolled in this study are to be monitored for safety and clinical outcomes through 5 years post-BRT-DA01 transplantation. For individual participating subjects, the Baseline visit for the BRT-DA01-501 study will be defined as the last observation recorded in the parent study.

Conditions

Timeline

Start date
2023-05-16
Primary completion
2027-05-01
Completion
2027-09-01
First posted
2023-06-12
Last updated
2024-04-12

Locations

3 sites across 2 countries: United States, Canada

Source: ClinicalTrials.gov record NCT05897957. Inclusion in this directory is not an endorsement.