NCT05896514

Carotis cFT In Prediction Of Hypotension

The Role of Carotis Flow Time in Prediction of Hypotension After Anesthesia Induction in Elderly Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 138 (actual)
• Sponsor: Cukurova University · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

The aim of our study is to determine the predictive value of pre-anesthesia FTc for hypotension that may develop after general anesthesia induction in patients over 65 years of age and to investigate the correlation between pre-anesthesia FTc and the magnitude of the maximum decrease in systolic blood pressure from the pre-anaesthetic value.

Detailed description

The FTc value of the patients to be included in the study will be measured by ultrasonography 10 minutes before the induction of anesthesia.After the measurement, the patients will be monitored with 3-lead electrocardiography, pulse oximetry and noninvasive blood pressure in the operating room. Before induction of general anesthesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MAP), oxygen saturation and heart rate will measured for 3 minutes at 1-minute intervals. Induction of anesthesia with 1-2 mg/kg propofol, muscle relaxation will be achieved with 0.6 mg/kg intravenous rocuronium. During mask ventilation, 1-2% concentration of sevoflurane and 50-50% oxygen-nitrous oxide will be used. After the anesthesia induction, SBP, DBP, MAP, oxygen saturation and heart rate will be measured for 3 minutes at 1-minute intervals. Hypotension; defined as a 30% reduction in SBP or a 20% reduction in MAP, or an absolute SBP below 90 mm Hg and MAP below 65 mm Hg within 3 minutes of induction of general anesthesia.Intravenous (iv) noradrenaline and/or iv crystalloid will be used in the treatment of hypotension.

Conditions

• Flow Time
• Carotid Doppler Ultrasound
• Hypotension
• Anesthesia
• Elderly

Interventions

Type	Name	Description
DEVICE	ultrasound-guided carotid artery flow time measurement	Ultrasound-guided corrected carotid artery flow time will be measured before anestesia induction.

Timeline

• Start date: 2023-06-03
• Primary completion: 2023-12-07
• Completion: 2023-12-07
• First posted: 2023-06-09
• Last updated: 2023-12-08

Locations

1 site across 1 country: Turkey (Türkiye)