Clinical Trials Directory

Trials / Completed

CompletedNCT05894928

A Study to Evaluate the Effect of Cholestyramine on LOXO-783 in Healthy Participants

A Phase 1 Study to Investigate the Effect of Cholestyramine on the Pharmacokinetics of LOXO-783 in Healthy Adults

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
21 (actual)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The main purpose of this study is to conduct blood tests to measure how much LOXO-783 is in the bloodstream and how the body handles and eliminates LOXO-783 when administered alone or in combination with cholestyramine in healthy participants. The study will also evaluate the safety and tolerability of LOXO-783 with and without cholestyramine. Participation could last up to 63 days including screening period.

Conditions

Interventions

TypeNameDescription
DRUGLOXO-783Administered orally.
DRUGCholestyramineAdministered orally.

Timeline

Start date
2023-06-07
Primary completion
2023-07-09
Completion
2023-07-09
First posted
2023-06-08
Last updated
2023-09-26

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05894928. Inclusion in this directory is not an endorsement.