NCT05891769

99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT

Evaluation of Patients With Suspected Parathyroid Adenoma and Negative or Equivocal 99mTc Sestamibi SPECT/CT Using 18F Fluorocholine PET/CT

• Status: Recruiting
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Andrei Iagaru · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study proposes the use of a well-established PET isotope, Fluorine-18 (18F), bound to Choline, for a prospective single-center, single-arm study for participants with suspected parathyroid adenoma and negative or equivocal standard of care 99mTc Sestamibi SPECT/CT

Conditions

• Parathyroid Adenoma

Interventions

Type	Name	Description
DRUG	18Fluorocholine	18F Fluorocholine 5 mCi ± 20% administered intravenously.

Timeline

• Start date: 2023-09-27
• Primary completion: 2026-07-01
• Completion: 2027-07-01
• First posted: 2023-06-07
• Last updated: 2025-09-10

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study