NCT05889546

Rapid Autopsy Protocol for Patients With Small Cell Lung Cancer

Rapid ("Warm") Autopsy Protocol for Patients With Small Cell Lung Cancer

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection.

Detailed description

The goal of this project to establish a rapid autopsy program in SCLC at the IUSCCC and outline the key components necessary for tumor tissue acquisition. This proposal is a collaboration between scientists, lung cancer physicians, pathologists, and the IUSCCC Translational Research Core. Tumor tissue collected will be used for protein and gene analysis and RNA, whole exome sequencing in addition to the establishment of SCLC. This research is part of a discovery project in which biological and molecular markers of SCLC will be identified.

Conditions

• Small Cell Lung Cancer

Interventions

Type	Name	Description
PROCEDURE	Biospecimen Collection	Lung, liver, skin, subcutaneous metastases, and blood specimens may be collected via rapid autopsy within 10 hours of expiration.

Timeline

• Start date: 2022-08-31
• Primary completion: 2030-12-31
• Completion: 2031-12-31
• First posted: 2023-06-05
• Last updated: 2025-07-20

Locations

3 sites across 1 country: United States