NCT05888168

Predictors of Postoperative Atrial Fibrillation After CABG

A Comprehensive Observational Study on the Determinants of Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 15,000 (estimated)
• Sponsor: Kun Hua · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.

Detailed description

Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.

Conditions

• Coronary Artery Disease
• Atrial Fibrillation New Onset

Interventions

Type	Name	Description
PROCEDURE	CABG	All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.

Timeline

• Start date: 2018-01-01
• Primary completion: 2023-12-15
• Completion: 2024-05-01
• First posted: 2023-06-05
• Last updated: 2023-06-05

Locations

1 site across 1 country: China