NCT05887778

Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery

Effect of Systematic Dexamethasone on the Duration of Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Poznan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 3 Months – 18 Years
• Healthy volunteers: Not accepted

Summary

Effect of Systematic Dexamethasone on the Duration of Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery

Detailed description

This study is proposed to explore the effect of systemic Dexamethasone on the duration of supraclavicular brachial plexus block for analgesia after pediatric ankle surgery. After hand and wrist surgery, children need good analgesia. Peripheral nerve blocks have provided a safe, effective method to control early postoperative pain when symptoms are most severe. The safety of local anesthesia is essential in children due to the much lower toxicity threshold of local anesthetics. An effective adjuvant, such as Dexamethasone, could allow for a higher dilution of local anesthetics while maintaining and enhancing their analgesic effect. There is considerable research where intravenous and perineural dexamethasone use has been compared in adults. However, there is a massive lack of research regarding children. In this study, investigators compare different doses of systemic Dexamethasone. Before the anesthesia, the patients receive Dexamethasone intravenously. Groups 2 and 3 have dexamethasone doses of 0.1mg/kg and 0.2mg/kg. The investigator's goal is to find a dexamethasone dose that is as low as possible but simultaneously covers the need for good pain relief and fast recovery postoperatively.

Conditions

• Wrist Disease
• Hand Injuries and Disorders

Interventions

Type	Name	Description
DRUG	Sodium Chloride 0.9% Inj	administration of 5ml 0,9% sodium chloride - 30 minutes before the supraclavicular brachial plexus block
DRUG	0,1mg/kg Dexamethasone	administration of 0,1mg/kg Dexamethasone - 30 minutes before the supraclavicular brachial plexus block
DRUG	0,2mg/kg Dexamethasone	administration of 0,2mg/kg Dexamethasone - 30 minutes before the supraclavicular brachial plexus block

Timeline

• Start date: 2023-09-18
• Primary completion: 2024-07-01
• Completion: 2024-08-01
• First posted: 2023-06-05
• Last updated: 2023-10-13

Locations

1 site across 1 country: Poland