NCT05885646

Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes

Treatment of Epilepsy Syndromes of Childhood With Sleep Activation Using Sulthiame: an Exploratory Study of the Short Term Effect on EEG

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 15 (estimated)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 6 Years – 15 Years
• Healthy volunteers: —

Summary

The effect of sulthiame on EEG has been studied in epilepsy syndromes of childhood with sleep activation by comparing sleep EEG obtained at baseline and after 4 weeks of treatment. The aim of the study is to know if an effect is still identifiable after 2 weeks of treatment by performing sleep EEG recordings after 2 and 4 weeks of treatment, respectively.

Conditions

• Importance of Interictal Epileptiform Activity on Sleep EEG
• Epilepsy in Children

Interventions

Type	Name	Description
DRUG	Sulthiame	Sulthiame add-on according to good clinical practice in these childhood epilepsy syndromes

Timeline

• Start date: 2023-10-17
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2023-06-02
• Last updated: 2025-06-15

Locations

3 sites across 1 country: France