NCT05882643

Deep Neuromuscular Blockade in Strabismus Surgery

The Effect of the Deep Neuromuscular Block on the Refraction and the Oculocardiac Reflex During Strabismus Surgery in Pediatric Patients - a Prospective Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 204 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 3 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if inducing a moderate or greater neuromuscular block (TOF count 0-3) when performing a neuromuscular block in pediatric patients aged 3 to 18 years undergoing strabismus surgery under general anesthesia can reduce the incidence of the oculocardiac reflex.

Conditions

• Strabismus

Interventions

Type	Name	Description
OTHER	moderate to deep neuromuscular blockade	* Maintaining moderate to deep neuromuscular blockade during an intraoperative period (Train-of-four 0-3 count, post-tetanic count \> 1) * Rocuronium (intravenous, 1.0 mg/kg at induction period)
OTHER	shallow to minimal neuromuscular blockade	* Maintaining shallow to minimal neuromuscular blockade during an intraoperative period (Train-of-four 4, post-tetanic count \< 0.9) * Rocuronium (intravenous, 0.3 mg/kg at induction period)

Timeline

• Start date: 2024-08-28
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2023-05-31
• Last updated: 2024-11-29

Locations

1 site across 1 country: South Korea