NCT05881252

Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension

An Observational Study of Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,003 (actual)
• Sponsor: The University of Texas Health Science Center, Houston · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is observe outcomes before and after a change in clinical practice in the threshold for management of severe hypertension in pregnancy and the post-partum period. Outcomes will be observed for 10 months under the current (traditional) clinical blood pressure threshold for acute treatment of hypertension, which is \>= 160 millimeters of mercury (mmHg) systolic blood pressure (SBP). This will be followed by one month of education about rationale for the new SBP threshold of \>= 180 mmHg and change of clinical guidelines. Then, there will be 10 months of observation after adopting the updated clinical threshold for acute antihypertensive treatment (\>= 180 SBP).

Conditions

• Maternal Hypertension

Interventions

Type	Name	Description
PROCEDURE	Clinical blood pressure threshold of SBP >= 160 mmHg for acute treatment of hypertension	Patients are treated for hypertension if SBP \>= 160 mmHg.
PROCEDURE	Clinical blood pressure threshold of SBP >= 180 mmHg for acute treatment of hypertension	Patients are treated for hypertension if SBP \>= 180 mmHg.

Timeline

• Start date: 2023-05-11
• Primary completion: 2024-04-04
• Completion: 2024-04-04
• First posted: 2023-05-31
• Last updated: 2025-07-28

Locations

1 site across 1 country: United States