Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05880680

SEAL™ME: Saccular Endovascular Aneurysm Lattice System Multicenter Enrollment Global Registry

Status
Recruiting
Phase
Study type
Observational
Enrollment
200 (estimated)
Sponsor
Galaxy Therapeutics INC · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Prospective, international, single-arm, multicenter, registry study. Patients presenting with evidence of Wide Neck unruptured or ruptured intracranial aneurysm (≤ 20 mm in widest diameter) requiring treatment will be enrolled into the study and treated using the SEAL™ System.

Detailed description

Prospective, international, single-arm, multicenter, registry study. Patients presenting with evidence of Wide Neck unruptured or ruptured intracranial aneurysm (≤ 20 mm in widest diameter) requiring treatment will be enrolled into the study and treated using the SEAL™ System. Immediate post-procedure angiographic findings, clinical presentation, safety, and optional imaging follow-up for each subject will be collected at 24 hours or discharge, 3 months, 6 months, and required primary end point 12 months post-procedure. DSA at 12 months will be required imaging for the primary effectiveness endpoint assessment. Subjects follow up will continue annually for a total of five years post procedure.

Conditions

Interventions

TypeNameDescription
DEVICESEAL DeviceUsing standard interventional endovascular techniques, the device is navigated via the push wire delivery system through compatible neurovascular microcatheters to the aneurysm lumen or target site. The device is positioned into its target aneurysm lumen and is electrically detached by the operator with a hand-held, battery-powered detachment handle designed specifically for the SEAL Embolization System.

Timeline

Start date
2023-10-09
Primary completion
2026-12-31
Completion
2030-06-15
First posted
2023-05-30
Last updated
2025-04-04

Locations

4 sites across 4 countries: Colombia, New Zealand, Pakistan, Spain

Source: ClinicalTrials.gov record NCT05880680. Inclusion in this directory is not an endorsement.