NCT05879237

Role of Vitamin D Supplementation as an Adjuvant Therapy inTreatment of Helicobacter Pylori in Children

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: 4 Years – 18 Years
• Healthy volunteers: Accepted

Summary

To study the efficacy of vitamin D in conjunction with Helicobacter pylori treatment in children in eradication of helicobacter pylori.

Detailed description

o study the efficacy of vitamin D in conjunction with Helicobacter pylori treatment in children in eradication of helicobacter pylori. our study include 2 patient groups: 1. st group included 100 child diagnosed Helicobacter pylori infection by upper gastrointestinal endoscopy and biopsies with pathology, will receive H.pylori eradication treatment and vitamin D as an adjuvant therapy . 2. nd group will also diagnosed Helicobacter pylori infection by upper gastrointestinal endoscopy and biopsies with pathology, will receive H.pylori eradication treatment only. Helicobacter pylori treatment : 1. amoxcillin on 50 mg/kg/day for 2 weeks 2. clarithromycin 20mg/kg/day for 2 weeks 3. proton pump inhibitor 1mg/kg/day for 1month Vitamin d dose..1000unit /day for 1 month

Conditions

• Helicobacter Pylori Infection

Interventions

Type	Name	Description
DRUG	Vitamin D3	Vitamin D3 ,1000 unit ,once daily, oral, for 1 month plus triple therapy
DRUG	Helicobacter pylori triple therapy	Triple therapy which is: amoxcillin on 50 mg/kg/day for 2 weeks, Clarithromycin 20mg/kg/day for 2 weeks and proton pump inhibitor 3.ppi 1mg/kg/day for 1month

Timeline

• Start date: 2023-06-01
• Primary completion: 2023-12-01
• Completion: 2023-12-10
• First posted: 2023-05-30
• Last updated: 2023-05-30