NCT05875584

Exploratory Study of a Novel Based rbcDNA Liquid Biopsy Technique for Colorectal Cancer Early Detection

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 598 (actual)
• Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University · Academic / Other
• Sex: All
• Age: 40 Years – 74 Years
• Healthy volunteers: Accepted

Summary

Exploration of a novel rbcDNA liquid biopsy technique for early detection of colorectal cancer is a promising development in the field of disease diagnosis and screening. This technique has the potential to establish an efficient and sensitive system for the early detection of colorectal cancer, which can provide a new perspective for individual health monitoring.

Detailed description

Patients who are at high risk of developing colorectal cancer and willing to undergo colonoscopy examination will be asked to collect a stool sample prior to bowel preparation for commercially available FIT (fecal immunochemical test) assay, as well as a blood sample for rbcDNA testing. The colonoscopy and histopathologic examination will be used as a reference for the results obtained from these tests.

Conditions

• Colorectal Cancer
• Adenomatous Polyps
• Adenoma
• Advanced Adenoma

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	rbcDNA test	fecal immunochemical test

Timeline

• Start date: 2023-05-18
• Primary completion: 2023-12-28
• Completion: 2024-01-10
• First posted: 2023-05-25
• Last updated: 2024-08-27

Locations

1 site across 1 country: China