NCT05874479

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 440 (estimated)
• Sponsor: NYU Langone Health · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Fine particulate matter \<2.5 µm (PM2.5) air pollution is the fifth leading risk factor for global mortality, with the largest portion of deaths due to cardiovascular disease (CVD). While several mechanisms are responsible, PM2.5-induced elevations in blood pressure (BP) may be relevant. Indoor portable air cleaners (PACs) are a novel approach to reduce exposure to PM2.5 and potentially lower blood pressure. The current study is being conducted to provide evidence that PACs reduce PM2.5 exposure and lower systolic blood pressure (SBP) in key patient populations.

Conditions

• Blood Pressure

Interventions

Type	Name	Description
DEVICE	Active PAC	The active PAC will contain HEPA filters inside the device.
DEVICE	Sham PAC	The sham PAC will contain no HEPA filters inside the device.

Timeline

• Start date: 2023-12-20
• Primary completion: 2027-09-01
• Completion: 2028-03-01
• First posted: 2023-05-25
• Last updated: 2025-10-01

Locations

1 site across 1 country: United States