NCT05869370

The Effects Of Low Intensity Training With Blood Flow Restriction In Rheumatoid Arthritis Patients

The Effects Of Low Intensity Training With Blood Flow Restriction In The Lower And Upper Limbs On Muscle Strength, Muscle Mass, Biochemical Parameters And Markers Of Systemic Inflammation In Rheumatoid Arthritis Patients: A Randomized Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (estimated)
• Sponsor: Federal University of Rio Grande do Sul · Academic / Other
• Sex: Female
• Age: 45 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Rheumatoid arthritis (RA) patients showed systemic manifestations that may lead to a reduction in muscle strength, muscle mass and, consequently, to a reduction in physical function. On the other hand, high intensity resistance training (HIRT) are able to improve muscle strength and muscle mass in RA without affecting the disease course. However, due to the articular manifestations caused by this disease, these patients may present intolerance to HIRT. Thus, the low intensity resistance training with blood flow restriction (TBFR) may be a new training strategy for these populations. In this sense, the investigators speculate that TBFR could be beneficial in RA patients, as well as, HIRT.

Conditions

• Rheumatoid Arthritis

Interventions

Type	Name	Description
OTHER	High intensity resistance training	Twelve weeks of resistance training twice a week.
OTHER	Low intensity resistance training combined with blood flow restriction	Twelve weeks of resistance training with blood flow restriction twice a week.

Timeline

• Start date: 2018-05-20
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2023-05-22
• Last updated: 2023-05-22

Locations

1 site across 1 country: Brazil