NCT05867342

Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In endoscopic sinus surgery a clear surgical field of view is a very important aspect for good surgical outcome. This study is to evaluate the preoperative preparation to acquire best surgical field of view by comparing between the use of topical adrenaline and the use of combination of topical adrenaline with infiltration of 1% lidocaine with adrenaline in patients scheduled for endoscopic sinus surgery for rhinosinusitis.

Conditions

• Intraoperative Bleeding

Interventions

Type	Name	Description
DRUG	Epinephrin	Topical application of 2 pieces of Epinephrin (1:1,000)-soaked cottonoid in nasal cavity
DRUG	1% lidocaine with epinephrin 1:100,000	4 ml intranasal infiltration of 1% lidocaine with epinephrine (1:100,000) at 2 sites (2 ml infiltration at each site)
DRUG	Saline	4 ml intranasal infiltration of saline at 2 sites (2 ml infiltration at each site)

Timeline

• Start date: 2017-05-12
• Primary completion: 2018-08-22
• Completion: 2018-08-22
• First posted: 2023-05-22
• Last updated: 2023-07-10
• Results posted: 2023-07-10

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study