NCT05867043

Postoperative Gastrointestinal Dysfunction After High Risk Surgery

Postoperative Gastrointestinal Dysfunction After High Risk Surgery: A Prospective Study in Adult Intensive Care Unit

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 66 (estimated)
• Sponsor: Aldy Heriwardito · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to find out the role of plasma I-FABP level, SOFA score, fluid balance, and vasopressor dose in predicting gastrointestinal dysfunction in high-risk postoperative patients treated in ICU

Detailed description

This is a prospective cohort study to find out the role of plasma I-FABP level, SOFA score, fluid balance, and vasopressor dose in predicting gastrointestinal dysfunction in high-risk postoperative patients treated in ICU. The characteristics of patients who meet the eligibility criteria were obtained. Blood sampling during admission is done for I-FABP level measurement and will be repeated after 24 hours. Blood sample which is not directly processed will be stored in refrigerator under 6-8C temperature. Evaluation of Acute Gastrointestinal Injury signs and symptoms is done. The re-evaluation is performed every day. If patients experiencing AGI signs and symptoms, monitoring and treatment based on condition are done. Routine follow-up is continued during hospitalisation in ICU. After all sample are collected, I-FABP level is assessed quantitatively using ELISA.

Conditions

• Gastrointestinal Dysfunction
• Surgery
• Postoperative Complications

Timeline

• Start date: 2023-01-23
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2023-05-19
• Last updated: 2023-05-19

Locations

1 site across 1 country: Indonesia