NCT05864183

Screening for Risk Factors of Prediabetes Among Adult Patients at Sohag University Hospital

Screening for Risk Factors of Prediabetes Among Adults Patients at Sohag University Hospital

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

* Prediabetes is an intermediate state of hyperglycemia with glycemic parameters above normal but below the diabetes threshold.. * during the average 3 years of follow-up Prediabetes is diagnosed based on laboratory tests: fasting plasma glucose level (100-125 mg/dl) ;HbA1c, (5.7-6.4%) or plasma glucose level after an oral glucose tolerance test ( 140-199 mg/dl). * Reports estimate that more than 470 million people will have prediabetes by 2030. * According to an expert panel of the American Diabetes Association, up to 70% of individuals with prediabetes will eventually develop diabetes. * Observational evidence suggests as association between prediabetes and complications of diabetes such early nephropathy(10%) , small fiber neuropathy(18-25 %), early retinopathy (8-12%) and risk of macrovascular disease (52%) . * Screening for prediabetes is designed to save lives or enhance an individual's quality of life by early detection so that screening will minimize the risk of developing diabetes or its complications .

Detailed description

* In this case control study we aim to screen for risk factors of prediabetes among adult patients to minimize the risk of developing diabetes or its complications . * Prediabetes screening is also required to minimize medical costs such as hospitalization, outpatient care, surgery, medications, and laboratory test costs . * Several studies had shown efficacy of lifestyle interventions in diabetes prevention by targeting obesity with increase in physical activity and dietary changes with a relative risk reduction of 40%-70% in adults with prediabetes ,also there is increasing evidence to prove the efficacy of pharmacotherapy in prevention of diabetes in adults with prediabetes

Conditions

• PreDiabetes

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	HbA1c	HbA1c will be measured for all patients to minimize the risk of developing diabetes or its complications .
DIAGNOSTIC_TEST	lipid profile	lipid profile will be measured for all patients to minimize the risk of developing diabetes or its complications .
DIAGNOSTIC_TEST	CBC	CBC will be measured for all patients to minimize the risk of developing diabetes or its complications
DIAGNOSTIC_TEST	Alb/cr ratio	Alb/cr will be measured for all patients to minimize the risk of developing diabetes or its complications
DIAGNOSTIC_TEST	serum creatinine .	serum creatinine will be measured for all patients to minimize the risk of developing diabetes or its complications
DIAGNOSTIC_TEST	CRP	CRP will be measured for all patients to minimize the risk of developing diabetes or its complications
DIAGNOSTIC_TEST	urine analysis	urine analysis will be measured for all patients to minimize the risk of developing diabetes or its complications
DIAGNOSTIC_TEST	ECG	ECG will be done for all patients to minimize the risk of developing diabetes or its complications
DIAGNOSTIC_TEST	fundus examination	fundus examination will be done for all patients to minimize the risk of developing diabetes or its complications

Timeline

• Start date: 2023-04-15
• Primary completion: 2023-12-01
• Completion: 2023-12-01
• First posted: 2023-05-18
• Last updated: 2023-05-18

Locations

1 site across 1 country: Egypt