NCT05864157

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: University of North Carolina, Chapel Hill · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to determine how training to step with a metronome on both a treadmill, as well as overground, will influence the way that people with Parkinson disease walk. Using metronomes is commonly used in clinics, but the investigators will be using a combination of slow and fast frequencies to alter the way that people walk. The use of a slower frequency metronome on the treadmill is intended to help participants take larger steps. The use of a faster frequency metronome while walking overground is intended to help participants take faster steps.This will take place over 12 training sessions. Each session will be about an hour. It will include some walking tests and pictures of the brain (using MRI) before and after training.

Detailed description

Some details regarding the metronome frequency are purposely omitted at this time to preserve scientific integrity. They will be included after the trial is complete

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
OTHER	Gait training without rhythmic auditory cues	Gait training on treadmill and overground without any rhythmic auditory cues
OTHER	TRAC	Metronome set to 85% on treadmill and 115% when walking overground
OTHER	dTRAC	Metronome set around 85% on treadmill and around 115% when walking overground

Timeline

• Start date: 2023-08-16
• Primary completion: 2026-05-01
• Completion: 2026-05-03
• First posted: 2023-05-18
• Last updated: 2025-11-06

Locations

1 site across 1 country: United States