NCT05860088

The Impact of Beef on Muscle Fatigue in Older Adults

The Effect of Beta-Alanine and Carnosine From Beef Intake on Muscle Fatigue in Older Adults

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 60 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The goal of this controlled-feeding cross-over diet intervention is to compare a beef diet to a vegetarian diet on muscle fatigue in older adults. The aims are: AIM 1: To test the hypothesis that muscle fatigue is attenuated in older adults consuming beef compared to older adults consuming a plant-based diet. AIM2: To test the hypothesis that daily beef consumption improves biochemical indicators related to muscle fatigue. Participants will be randomized to consume either a beef-based diet or vegetarian diet under controlled-feeding conditions for 8 weeks. After a 2-week washout period, participants will cross-over to consume either the beef diet or vegetarian diet for 8 weeks. Body composition and functional muscle outcomes will be measured during each 8-week feeding period. Blood samples will also be collected.

Conditions

• Muscle Weakness
• Muscle; Fatigue, Heart
• Older Adults

Interventions

Type	Name	Description
OTHER	Beef Diet	Controlled-Feeding Diet Intervention
OTHER	Vegetarian Diet	Controlled-Feeding Diet Intervention

Timeline

• Start date: 2023-07-10
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2023-05-16
• Last updated: 2024-02-09

Locations

1 site across 1 country: United States