NCT05859646

Effects of Probiotics on Streptococcus Mutans ve Lactobacillus Spp

Evaluation of Streptococcus Mutans and Lactobacillus Species Due to Probiotic Use in Oral Flora

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: Didem Sakaryali Uyar · Academic / Other
• Sex: All
• Age: 2 Years – 12 Years
• Healthy volunteers: Accepted

Summary

To evaluate the change of S. mutans and Lactobacillus spp. counts after all dental treatments were completed under general anesthesia and compare the groups in case of using probiotics and not using probiotics with the time for 6-months follow-up period.

Detailed description

Fifthy-eight pediatric patients without any systemical diseases whose dental treatments were completed under general anesthesia were included in the study. The study was carried out as two-groups; Group A: Patients who started using probiotics after general anesthesia and Group B: Patients who did not use probiotics after general anesthesia. The counts of S. mutans and Lactobacillus spp. were determined by quantitative polymerase chain reaction (qPCR) by analysis of saliva samples taken from all patients on the day before the general anesthesia (T0), at 1-month (T1), 3-month (T2) and 6-month (T3) follow-up periods. The statistical significance level was accepted as p\<0.05.

Conditions

• Tooth Decay
• Probiotics
• Streptococcus Mutans

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic use	Probiotics were used for 3 months and all participated patients were followed for 6 months.

Timeline

• Start date: 2020-01-15
• Primary completion: 2022-01-15
• Completion: 2022-05-15
• First posted: 2023-05-16
• Last updated: 2023-05-16

Locations

1 site across 1 country: Turkey (Türkiye)