Trials / Recruiting
RecruitingNCT05857150
Exercise Response in Humans With Obesity
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 120 (estimated)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- All
- Age
- 20 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
This study is being done to understand how chronic inflammation affects muscle function and responses to exercise.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Treadmill Test | Measurement of whole-body fitness level. Walking or running on a treadmill and breathing into a machine that measures oxygen level during test. Heart rhythm is continuously monitored during exercise using an electrocardiogram (ECG). |
| DIAGNOSTIC_TEST | Strength Test | Measure the strength of leg muscles by kicking against a machine with resistance. |
| DIAGNOSTIC_TEST | Dual-Energy X-Ray Absorptiometry | Body composition measurement. |
| PROCEDURE | Muscle Biopsy | Obtain a small piece of muscles from the upper part of the legs |
| PROCEDURE | Fat Biopsy | Fat sample taken from abdomen |
| DIAGNOSTIC_TEST | Resting Energy Expenditure | Measured by indirect calorimetry. Measures how much energy the body uses at rest by placing a special plastic dome over the head while resting quietly for 30 minutes. Measures oxygen breathed in and carbon dioxide breathed out. |
| DIAGNOSTIC_TEST | Magnetic resonance imaging | MRI on upper leg to look at fat and muscle |
Timeline
- Start date
- 2023-09-22
- Primary completion
- 2029-07-01
- Completion
- 2029-07-01
- First posted
- 2023-05-12
- Last updated
- 2025-08-29
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05857150. Inclusion in this directory is not an endorsement.