Clinical Trials Directory

Trials / Unknown

UnknownNCT05856409

Clinical Application of 68Ga-FAPI PET Imaging in Detection of Ovarian Cancer Recurrence

Status
Unknown
Phase
Study type
Observational
Enrollment
20 (estimated)
Sponsor
RenJi Hospital · Academic / Other
Sex
Female
Age
18 Years – 80 Years
Healthy volunteers

Summary

This is a prospective study to investigate the potential efficacy of 68Ga-FAPI PET/CT for recurrence detection of epithelial ovarian cancer in comparison with 18F-FDG PET/CT.

Detailed description

Gallium 68-labeled fibroblast-activation protein inhibitor (68Ga-FAPI) has recently been a potential radiotracer for gynecological malignancies,including ovarian cancer. Early detection and localization of sites of recurrence helps to identify ovarian cancer patients who will benefit the most from secondary surgery, chemotherapy, or radiation therapy. Its clinical utility for recurrence detection of epithelial ovarian cancer and histological validation of FAPI findings is not well established.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TEST68Ga-FAPI\[68Ga\]-FAPI is tumor imaging agent for use with Positron Emission Tomography (PET) imaging for the detection of Fibroblast Activation Protein (FAP) positive cancer cells and cancer-associated fibroblasts (CAF)

Timeline

Start date
2023-05-10
Primary completion
2024-04-01
Completion
2025-12-31
First posted
2023-05-12
Last updated
2023-08-16

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05856409. Inclusion in this directory is not an endorsement.

Clinical Application of 68Ga-FAPI PET Imaging in Detection of Ovarian Cancer Recurrence (NCT05856409) · Clinical Trials Directory