NCT05850650

The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis

The Effect of Collagen Sponge Placed in the Socket After Surgical Extraction of Mandibular Third Molars on the Incidence of Alveolar Osteitis. A Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Riyadh Colleges of Dentistry and Pharmacy · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures. Collagen plugs will be applied in the sockets of the study side followed by suture, while the controlled side will be sutured without a collagen plug. The study will include 40 patients aged between 18- 40 years old, medically fit (ASA1), who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction. The main question is" Does intra-alveolar collagen application after surgical extraction of impacted lower third molars reduce the incidence of alveolar osteitis?

Conditions

• Alveolar Osteitis

Interventions

Type	Name	Description
OTHER	Application of a collagen sponge after surgical extraction of impacted 3rd molar	Application of a collagen sponge after surgical extraction of impacted 3rd molar
OTHER	No collagen sponge application after surgical extraction of impacted 3rd molar	No collagen sponge application after surgical extraction of impacted 3rd molar

Timeline

• Start date: 2023-05-01
• Primary completion: 2023-10-15
• Completion: 2023-11-15
• First posted: 2023-05-09
• Last updated: 2023-05-09

Locations

1 site across 1 country: Saudi Arabia