NCT05845736

The Impact of Dementia and Neurocognitive Disorders on Hypertension Treatment in the Elderly

The Impact of Dementia and Neurocognitive Disorders on Hypertension Treatment in the Very Elderly: the TAHOC Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 353 (actual)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 80 Years
• Healthy volunteers: Not accepted

Summary

Neurocognitive disorders and hypertension occur commonly with aging. While, by definition, older adults are at high cardiovascular risk, there is no guideline exist currently on blood pressure management of elderly hypertension. However, studies have shown that in aging adults, high blood pressure helps prevent against cognitive decline, and low blood pressure on antihypertensive drugs could accelerate it. This study aims at investigating if pharmacological treatment of hypertension in the very elderly is influenced by presence and severity of neurocognitive disorders. Our research hypothesis is that the drug management of hypertension in patients 80 years of age or older more is all the less aggressive as the neurocognitive disorders are advanced.

Conditions

• Neurocognitive Disorders
• Dementia
• Hypertension
• Aged, 80 and Over

Interventions

Type	Name	Description
DRUG	Antihypertensive Agents	number of hypertensive drugs

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-01-01
• Completion: 2022-12-12
• First posted: 2023-05-06
• Last updated: 2023-05-06

Locations

1 site across 1 country: France