NCT05845385

Postoperative Pain Relief After Major Abdominal Gynecological Surgery

Comparison of Lumbar Epidural Analgesia, Transversus Abdominis Plane Block and Wound Infiltration for Postoperative Pain Relief in Major Abdominal Gynecological Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 81 (actual)
• Sponsor: Cukurova University · Academic / Other
• Sex: Female
• Age: 18 Years – 69 Years
• Healthy volunteers: Accepted

Summary

The aim of our study was to compare the effects of Lomber Epidural Analgesia (LEA), Transversus Abdominis Plane (TAP) block and Local Anesthetic Infiltration (LAI) on postoperative morphine consumption, time to first recue analgesic request, pain and patient satisfaction scores and side effects were compared in the patients undergoing major gynecologic/oncology lower abdominal surgery.

Detailed description

Following faculty ethical committee approval and written informed consent, 81 patients were included in our prospective, randomized and double-blind study. Patients were divided into 3 groups: lumbar epidural block (Group E), TAP block (Group T), and wound infiltration (Group I). Demographic data, surgical characteristics, hemodynamic values, pain scores at rest and on movement, morphine consumption, additional analgesic requirement, side effects at 1, 2, 6, 12, 24, 36 and 48th hours after surgery, and patient satisfaction scores at 24 and 48th hours were recorded.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
PROCEDURE	lumbar epidural analgesia with bupivacaine	postoperative analgesic method
PROCEDURE	transversus abdominis plane block with bupivacaine	postoperative analgesic method
PROCEDURE	wound infiltration with bupivacaine	postoperative analgesic method

Timeline

• Start date: 2024-05-06
• Primary completion: 2024-08-01
• Completion: 2024-09-01
• First posted: 2023-05-06
• Last updated: 2024-09-19

Locations

2 sites across 1 country: Turkey (Türkiye)