Clinical Trials Directory

Trials / Terminated

TerminatedNCT05844826

Evaluation of the Microbiome in Multiple Sclerosis

A Clinical Study To Evaluate Small Intestine Microbiome In Multiple Sclerosis (MS)

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
40 (actual)
Sponsor
Nimble Science Ltd. · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Accepted

Summary

To access the small intestinal microbiome and find abnormal microbiome/metabolome signature in luminal fluid samples from small bowel in MS compared to HC that could be used as biomarkers for MS.

Detailed description

Participants will be swallowing the SIMBA capsule which allows for minimally-invasive sampling of the microbiome and metabolome deep in the small intestine. Researchers will use the capsule samples to access the small intestinal microbiome and find abnormal metabolomic signatures in luminal fluid samples from the small bowel in Multiple Sclerosis (MS) patients compared to healthy control.

Conditions

Interventions

TypeNameDescription
DEVICESIMBA CapsuleParticipants will swallow capsule

Timeline

Start date
2023-06-26
Primary completion
2024-04-24
Completion
2024-04-24
First posted
2023-05-06
Last updated
2025-05-15

Locations

1 site across 1 country: Canada

Source: ClinicalTrials.gov record NCT05844826. Inclusion in this directory is not an endorsement.