NCT05843617

Comparison of Bioavailability of Liposomal and Traditional Formulation of Vitamin C

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: AronPharma Sp. z o. o. · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The aim of the study was to compare the profiles of vitamin C serum concentration in healthy volunteers after the single oral administration either in a liposomal or traditional formulation.

Detailed description

The randomized, double-blind, cross-over study was conducted under the supervision of physician on a group of 10 healthy subjects. The volunteers received 1g of vitamin C in a traditional formulation (powder in capsules), and after 14 days of a washout period 1 gram of liposomal formulation (powder in capsules). Venous blood was collected from each participant of the study immediately before the administration of a studied substance and 30 minutes, 1 hour, 2 hours, 3 hours, 4 hours, 6 hours, 8 hours, 10 hours, 24 hours post the administration.

Conditions

• Bioavailability of Vitamin C

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Liposomal Vitamin C	1000 mg of ascorbic acid in liposomal formulation
DIETARY_SUPPLEMENT	Traditional Vitamin C	1000 mg of ascorbic acid in traditional formulation

Timeline

• Start date: 2022-02-28
• Primary completion: 2022-06-09
• Completion: 2022-06-09
• First posted: 2023-05-06
• Last updated: 2024-08-01

Locations

1 site across 1 country: Poland