NCT05843214

Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements

Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements in Postoperative Resuscitation Neurosurgery

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 230 (estimated)
• Sponsor: Centre Hospitalier Universitaire de la Réunion · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring with the aim, among others, of detecting episodes of intracranial hypertension, each method allowing the study of one of the different pathophysiological mechanisms of its impact. However, at present there is no data in the literature on the value of these non-invasive neuromonitoring tools in the management of patients undergoing controlled intracranial surgery. The study aims to help the early detection of postoperative neurological deterioration.

Conditions

• Neurological Complication

Interventions

Type	Name	Description
OTHER	Non-invasive neuromonitoring evaluation (transcranial doppler, optic nerve envelope diameter and quantitative pupillometry)	4 days Post-operation follow-up. Data will be gathered before the surgery and at regular times after the surgery until day 4

Timeline

• Start date: 2023-02-10
• Primary completion: 2026-02-09
• Completion: 2026-06-09
• First posted: 2023-05-06
• Last updated: 2023-05-06

Locations

1 site across 1 country: Reunion