Clinical Trials Directory

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UnknownNCT05840029

VATS IN PATIENTS WITH ADVANCED OVARIAN MALIGNANCIES

THE ROLE OF VIDEO-ASSISTED THORACOSCOPIC SURGERY IN PATIENTS WITH ADVANCED OVARIAN MALIGNANCIES

Status
Unknown
Phase
Study type
Observational
Enrollment
68 (actual)
Sponsor
Alexandria University · Academic / Other
Sex
Female
Age
20 Years – 80 Years
Healthy volunteers

Summary

Ovarian cancer is the seventh most common cancer and the fifth leading cause of death in women worldwide. About 70% of patients with epithelial ovarian cancer present with advanced disease which will require a combination of cytoreductive surgery and chemotherapy to give them their best chance of long term survival.The presence of macroscopic pleural disease-especially if undetected and unresected after primary debulking surgery-may alter treatment decision-making and markedly affect survival. Video-Assisted Thoracoscopic Surgery (VATS) allows surgeons, through a minimally invasive approach, to not only drain the pleural effusion but also evaluate macroscopic pleural disease and, when possible, resect gross tumor. Few studies reported that VATS altered the therapeutic management in ovarian cancer patients leading to an upstaging or down-staging when compared to the CT staging. Therefore, this study will prospectively assess the role of VATS in the diagnosis and management of supradiaphragmatic disease as well as evaluate the impact of VATS findings on the decision of surgical management in patients with advanced ovarian cancer FIGO (The International Federation of Gynecology and Obstetrics) stage III/IV.

Conditions

Interventions

TypeNameDescription
PROCEDUREVIDEO-ASSISTED THORACOSCOPIC SURGERYA minimally invasive approach, to not only drain the pleural effusion but also evaluate macroscopic pleural disease and, when possible, resect gross tumor.

Timeline

Start date
2021-06-01
Primary completion
2023-01-30
Completion
2023-04-30
First posted
2023-05-03
Last updated
2023-05-03

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT05840029. Inclusion in this directory is not an endorsement.