NCT05839756

Predicting Post Extubation Stridor After Maxillomandibular Fixation

Predicting Post Extubation Stridor in Patients With Intermaxillary Fixation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 62 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Endotracheal intubation can induce laryngotracheal injury which results in narrowing of the airway due to edema of the glottis. This can increase the risk of development of post-extubation stridor (PES)

Detailed description

Ultrasound (US) is a useful and non-invasive tool for the evaluation of vocal cords and laryngeal morphology in intubated patients. The laryngeal air-column width (LACW), Laryngeal air column width difference (LACWD), and laryngeal air-column width ratio (LACWR) measured by ultrasound can potentially identify patients at risk of post-extubation stridor, in whom caution should be taken after extubation. The cuff-leak test can predict successful extubation through using the difference between the expired tidal volume with the cuff inflated and with the cuff deflated; the higher the leak, the lower the likelihood that post-extubation stridor will occur.

Conditions

• Stridor
• Larynx Edema

Interventions

Type	Name	Description
DRUG	budesonide	2 ml nebulized budesonide (containing 1 mg) diluted in 3 ml of normal saline will be nebulized preoperatively
DRUG	normal saline	5 ml normal saline will be nebulized preoperatively

Timeline

• Start date: 2023-05-03
• Primary completion: 2028-02-25
• Completion: 2028-06-30
• First posted: 2023-05-03
• Last updated: 2026-02-17

Locations

1 site across 1 country: Egypt