Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05839392

Novel Approaches to Target MECOM/EVI1 in AML

Novel Approaches to Target MECOM/EVI1 in Acute Myeloid Leukemia

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
Gruppo Italiano Malattie EMatologiche dell'Adulto · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an academic, no-profit, multicenter, biological, non-pharmacologic study aimed at characterizing genome, transcriptome and proteome of patients affected by AML with MECOM or atypical 3q26 rearrangements.

Detailed description

This is an academic, no-profit, multicenter, biological, non-pharmacologic study aimed at characterizing genome, transcriptome and proteome of patients affected by AML with MECOM or atypical 3q26 rearrangements. To this end, BM samples and formalin fixed/paraffin-embedded BM biopsies will be collected at enrolment, before and after treatment, at relapse.

Conditions

Interventions

TypeNameDescription
BIOLOGICALBiological characterization of AML with MECOM or atypical 3q26 rearrangementsPeripheral blood and bone marrow withdrawal

Timeline

Start date
2023-12-13
Primary completion
2026-12-01
Completion
2026-12-01
First posted
2023-05-03
Last updated
2023-12-29

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT05839392. Inclusion in this directory is not an endorsement.