Clinical Trials Directory

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UnknownNCT05837689

Minimal Residual Disease Quantification by Next-generation Sequencing in Pediatric B-ALL Children Patients Treated With Blinatumomab Consolidation

Status
Unknown
Phase
Study type
Observational
Enrollment
20 (estimated)
Sponsor
Xiaojun Xu · Academic / Other
Sex
All
Age
1 Year – 18 Years
Healthy volunteers
Not accepted

Summary

A retrospective analysis to investigate pediatric B-cell acute lymphoblastic leukemia patients who were treated with blinatumomab for consolidation, and who were detected as minimal residual disease (MRD) positive by next generation sequencing (NGS). The efficacy of blinatumomab clearing MRD detected by NGS will be analyzed, in order to see the potential of using NGS to guide MRD eradication by blinatumomab.

Conditions

Interventions

TypeNameDescription
DRUGBlinatumomabIV

Timeline

Start date
2023-04-01
Primary completion
2023-04-01
Completion
2023-04-01
First posted
2023-05-01
Last updated
2023-05-01

Regulatory

Source: ClinicalTrials.gov record NCT05837689. Inclusion in this directory is not an endorsement.