NCT05835700

The Relationship Between Serum Gasdermin-D Levels and Pyroptosis and Preterm Labor

Research of the Relationship Between Serum Gasdermin-d Levels and Pyroptosis and Preterm Labor

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 327 (actual)
• Sponsor: Sanliurfa Mehmet Akif Inan Education and Research Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

In this study, the investigators aimed to investigate the relationship between Gasdermin D levels measured from the maternal serum of patients diagnosed with preterm labor and spontaneous preterm labor in pregnant women.

Detailed description

This prospective case- control study was conducted between 15 July 2021 and 15 July 2022 at Bursa Yüksek İhtisas Training and Research Hospital. The study was conducted with pregnant women between the ages of 18-45 who were idiopathic preterm labor. Pregnant women between the ages of 18-45 who were diagnosed with preterm labor between 24-37 weeks of gestational were included. This study was conducted with 160 pregnant women who were diagnosed with idiopathic preterm labor and 167 healthy pregnant women who were in the same gestational week as these pregnant women and were not diagnosed with preterm labor. Group 1 patients diagnosed with preterm labor between 24-37 weeks( study group) (n:160), Group 2 consisted of healthy pregnant women who were not diagnosed with preterm labor between 24-37 weeks ( control group) (n: 167) . In group 1, 80 patients were diagnosed with early preterm (between 24-34 weeks ) and 80 patients with late preterm labor (34-36+6 weeks).

Conditions

• Gasdermin D Levels in Preterm Labor

Interventions

Type	Name	Description
OTHER	Gasdermin-d	Maternal serum Gasdermin-D levels in preterm labor and healthy pregnant women.

Timeline

• Start date: 2021-07-15
• Primary completion: 2022-07-15
• Completion: 2022-07-15
• First posted: 2023-04-28
• Last updated: 2023-04-28

Locations

1 site across 1 country: Turkey (Türkiye)