NCT05835401

Effects of Dietary Nitrate Intake on Cardiovascular Performance in Response to Hand Grip Test in Bodybuilders

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: Male
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Through a randomized, crossover, double-blind, placebo-controlled clinical trial, 20 bodybuilders will participate a acute-day trial with two intervention protocols: 1) placebo and 2) nitrate; in which will ingest beet juice with or without NO3 in its composition with a 7-day washout interval.

Conditions

• Steroid Abuse
• Cardiovascular Abnormalities

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Beetroot juice rich in nitrate	The participant will intake beetroot juice rich in NO3 (800mg). Two hours after intake the last bottle of juice, the participants will go to the laboratory for the handgrip and cardiovascular tests evaluation. Before crossover protocol a 7-day washout interval will be given for the purification of the compounds provided by the protocols.
DIETARY_SUPPLEMENT	Beetroot juice depleted in nitrate	The participant will intake beetroot juice depleted in NO3. Two hours after intake the last bottle of juice, the participants will go to the laboratory for the handgrip and cardiovascular tests evaluation. Before crossover protocol a 7-day washout interval will be given for the purification of the compounds provided by the protocols.

Timeline

• Start date: 2023-04-17
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2023-04-28
• Last updated: 2025-07-28

Locations

1 site across 1 country: Brazil