NCT05830929

Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: Female
• Age: 1 Month – 35 Years
• Healthy volunteers: Not accepted

Summary

Ovarian Tissue Cryopreservation will be provided to cancer patients to allow them to have their fertility preserved.

Detailed description

This project hopes to provide Ovarian Tissue Cryopreservation to patients who do not have adequate time for ovarian stimulation in oocyte or embryo freezing and in prepubertal girls where oocyte freezing is not possible. All the patients will have fertility preservation consultations with a fertility specialist in our unit to go through the details of ovarian Tissue Cryopreservation service and risks related to ovarian tissue cryopreservation procedures. After undergoing ovarian tissue collection via surgery, the collected ovarian tissue will be cryopreserved either by slow freezing or vitrification in our unit.

Conditions

• Neoplasms

Interventions

Type	Name	Description
PROCEDURE	Ovarian tissue freezing and subsequent auto-transplantation after thawing	Removal of the ovarian tissue will be retrieved via laparoscopic surgery under general anesthesia. The ovarian cortical tissue obtained will be transferred on ice to the laboratory for cryopreservation. After medical treatment, if the patient would like to start a family but has experienced premature ovarian failure, she will have ovarian tissue auto-transplantation after thawing.

Timeline

• Start date: 2023-08-01
• Primary completion: 2043-04-30
• Completion: 2043-12-30
• First posted: 2023-04-26
• Last updated: 2026-01-07

Locations

1 site across 1 country: Hong Kong